Vertical Diffusion Cell Test System: HDT 1000

    With a precision dry heating system and integrated powerful magnetic stirrers, the compact HDT 1000 vertical diffusion cell tester from Copley has become the benchmark system for many labs. Using an innovative heating block approach, the HDT 1000 eradicates the difficulties and the “spaghetti” of tubing associated with water-jacketed cell systems and accommodates either endpoint or discrete manual sampling techniques. A dedicated stirrer mounted beneath each station ensures thorough mixing throughout testing for accurate sampling.

Features:

  • USP and compliant
  • Innovative dry heat system removes hassle and ‘spaghetti’ of tubing associated with water-based heating system
  • Precision control over all test parameters
  • Novel cell clamps simplify cell preparation
  • Powerful magnetic stirrers ensure consistent mixing during testing
  • HDT unit footprint is smaller than an A4 piece of paper

Specifications:

  • Pharmacopoeial Compliance: USP <1724>
  • Cell Capacity: Up to 10 vertical diffusion cells
  • Cell Types Supported: B, C and Skin
  • Heating System: Dry heating block
  • Sampling Technique Compatibility: Endpoint, Discrete, Fully automatic
  • Unit Dimensions (w x d x h): 80 x 325 x 145 mm

Accessories:

Cells: Type ‘B’ and ‘C’

Copley’s Type ‘B’ and ‘C’ cells feature a unique clamping system to simplify cell preparation and sample collection procedures. Cells are supplied complete with individual cell tops for both ‘closed or occluded’ operation (as per USP Model ‘A’) and ‘open’ operation (as per USP Models ‘B’ and ‘C’ respectively, maximising the versatility of the HDT 1000 and HDT-1 systems.

 

Cells: Skin

To accommodate ‘full thickness’ membranes or skin, a new screw-type cell closure mechanism has been developed for the skin specific cell that ensures proper contact between the sample and the receptor medium. All components of the cell are made from FDA-approved inert materials and a side sampling arm facilitates easy filling, sample withdrawal and media replacement.

 

Degassing

The Vacuum Deaeration Apparatus Model, VDA, from Copley is an easy-to-use and inexpensive unit designed to degas receptor medium prior to its use, ensuring that diffusion is unimpeded by the collection of gas beneath the membrane.